Jack Gugel

B.A. in Biophysics & Policy Studies, Syracuse University, 2018

I am studying Laing Distal Myopathy (MPD1), an inherited condition that causes progressive muscle weakness in the extremities and has no cure. MPD1 is caused by mutations in β-myosin, the primary contractile protein in cardiac and slow twitch skeletal muscle. My first goal is to learn how these mutations lead to disease. My second goal is to evaluate potential therapeutics for MPD1.