Ph.D. in Microbiology, Duke University, 1993
B.A. in Molecular, Cellular and Developmental Biology, University of Colorado Boulder, 1983.
I work on everything related to recombinant adenoviral expression vectors. Much of the research done in the Leinwand Lab involves transducing genes of interest into either Neonatal Rat Ventricular Myocytes, Adult Rat Ventricular Myocytes, or C2C12 Myotubes. Recombinant adenoviral expression vectors represent one of the most efficient delivery systems for transducing these cell types. However, the engineering and generation of these recombinant adenoviral expression vectors is a fairly complicated and drawn out process that I have spent the last 20 years perfecting so that it is a relatively straightforward process. I have recently been involved in helping produce the raw materials for recombinant sarcomeric myosin motor domain isolation for use in crystallographic studies.