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Saad Ansari defended his thesis

July 6, 2022

Congratulations to Saad Ansari for successfully defending his PhD thesis today.

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Shane Fiorenza defended his thesis

May 18, 2022

Congratulations to Shane Fiorenza for successfully defending his PhD thesis today.

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Crosslinker theory paper published in EPJE

March 29, 2021

Our paper "Comparison of explicit and mean-field models of cytoskeletal filaments with crosslinking motors" was published in European Physical Journal E today.

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Comparison of explicit and mean-field models of cytoskeletal filaments with crosslinking motors

Nov. 16, 2020

We explore different types of analytic models for crosslinkers and compare them to simulation.

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Adam Lamson defended his thesis

May 28, 2020

Congratulations to Adam Lamson for successfully defending his PhD thesis today.

Chromosome segregation in the model and comparison to experiments

Chromosome biorientation modeling paper published in eLife

Feb. 13, 2020

Our paper " Mechanisms of chromosome biorientation and bipolar spindle assembly analyzed by computational modeling " was published in the Feb 13, 2020 edition of eLife today.

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Chromosome biorientation modeling paper posted to bioRxiv

June 5, 2019

Our paper "Mechanisms of chromosome biorientation and bipolar spindle assembly analyzed by computational modeling" was posted on the bioRxiv server.

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Mechanisms of chromosome biorientation and bipolar spindle assembly analyzed by computational modeling

June 4, 2019

We develop a computational model of fission-yeast mitosis using a course-grained Brownian Dynamic framework in conjunction with a force-dependent kinetic Monte Carlo algorithm to replicate the biorientation and segregation of chromosomes.

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Cross-linker-mediated spindle assembly theory paper published in Biophysical Journal

May 7, 2019

Our paper " Theory of Cytoskeletal Reorganization during Cross-Linker-Mediated Mitotic Spindle Assembly " was published in the May 7, 2019 edition of Biophysical Journal. Our video was highlighted on the front page of the journal's website .

Model overview

Theory of cytoskeletal reorganization during crosslinker-mediated mitotic spindle assembly

May 7, 2019

We develop a torque-balance model that describes spindle assembly due to dynamic microtubule bundles, spindle-pole bodies, the nuclear envelope, and crosslinkers to predict spindle-assembly dynamics.

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