We develop a computational model of fission-yeast mitosis using a course-grained Brownian Dynamic framework in conjunction with a force-dependent kinetic Monte Carlo algorithm to replicate the biorientation and segregation of chromosomes.
Our paper " Theory of Cytoskeletal Reorganization during Cross-Linker-Mediated Mitotic Spindle Assembly " was published in the May 7, 2019 edition of Biophysical Journal. Our video was highlighted on the front page of the journal's website .
We develop a torque-balance model that describes spindle assembly due to dynamic microtubule bundles, spindle-pole bodies, the nuclear envelope, and crosslinkers to predict spindle-assembly dynamics.
Our paper "Theory of cytoskeletal reorganization during crosslinker-mediated mitotic spindle assembly" was accepted for publication at Biophysical Journal.
Our paper "Theory of cytoskeletal reorganization during crosslinker-mediated mitotic spindle assembly" was posted on the biorxiv preprint server today.
Members of the group went to the mountains for hiking and the group research retreat. We identified a promising location for our new headquarters (see photo).
