Connect with the 2025 Destination Startup companies

Avesta76 is a revolutionary biotech company that is developing cancer medications that can treat over half of all cancers safely and effectively. To do that, we have found the key to bypassing p53 mutations and deletions. We will begin first in-human clinical trials in early 2026. Visit the Avesta76 Website

• Raising: $25 Million Seed
• Contact: Ian Akash Morrison, akash@avesta76.com
• Team:Ian Akash Morrison*, Co-Founder, CEO; Sanjay Awasthi, M.D., Co-Founder, Chief Research Officer; Arjun Awasthi, Co-Founder, COO
• Affiliation: Texas Tech University System
• Industry Applications: Health and Wellness, Biotech, Artificial Intelligence (AI) and Machine Learning, Therapeutics

Cascade Bio empowers enzymes to change how molecules are made. Our product extends enzyme lifespans in chemical processes, lowering the cost of sustainable biomanufacturing. Over 20 companies have paid to try our product across pharmaceuticals, foods, recycling, specialty chemicals and biomining. Visit the Cascade Bio Website

• Raising: $5 Million Seed
• Contact: Alex Rosay, alex@cascadebio.com
• Team:Alex Rosay*, Co-Founder, CEO; James Weltz (Alum: CU Boulder Chemical and Biological Engineering), Co-Founder, CSO
• Affiliation: University of Colorado Boulder
• Industry Applications: Advanced Materials, Artificial Intelligence (AI) and Machine Learning, Environment and Sustainability, Cleantech, Food and Agriculture, Biotech

EerDx uses earbud sleep diagnostics to transform how we diagnose and treat the 100 million Americans with sleep disorders. By delivering advanced clinical-grade sensors in a consumer earbud factor that a patient can easily use at home, EerDx is making home sleep testing cool! Visit the EerDx website

• Raising: $1 Million Pre-Seed
• Contact: Bart Emery, bart@eerdx.com
• Teams:Bart Emery*, CEO, Co-Founder; Samir Chabra, CTO, Co-Founder
• Affiliation: University of Colorado Boulder
• Industry Applications: Advanced Materials, Artificial Intelligence (AI) and Machine Learning, Sensors, Health and Wellness, Medical Devices, Diagnostics

Flow Aluminum develops Aluminum-CO₂ batteries for grid storage, microgrids and defense, offering extreme temperature performance (-40°C to 170°C), enhanced safety and CO₂ utilization. Safer and cheaper than lithium-ion, our rechargeable system enables carbon removal and sustainable energy storage at scale. Visit the Flow Website

• Raising: $8 Million Seed
• Contact: Thomas Chepucavage, tom@flowaluminum.com
• Team: Chris Fetrow, Co-Founder, Chief Scientist; Tom Chepucavage, Co-Founder, CEO; Simit Shah, COO/CFO
• Affiliation: University of New Mexico
• Industry Applications: Aerospace, Advanced Materials, Civic Engagement and Government, Construction, Environment and Sustainability, Cleantech, Hardware and Instrumentation, Robotics, Sensors, Software, Manufacturing, Chemicals, Additive Manufacturing, Quantum, Research and Exploration, Social Enterprise, Smart Cities

Illumen Therapeutics is pursuing a p53 moonshot to transform cancer treatment by pioneering the development of PARN inhibitor drugs that increase functional p53, known as the 'Guardian of the Genome,' to treat aggressive cancers and improve patient survival. Visit the Illumen Website

• Raising: $5 Million Seed
• Contact: Bob Blomquist, bob@illumentx.com
• Team: Bob Blomquist*, CEO, Co-Founder; Roy Parker (CU Boulder BioFrontiers Institute), Co-Founder, Advisor; Brian Williams, CFO; Jim Winkler, Interim CSO
• Affiliation: University of Colorado Boulder
• Industry Applications: Health and Wellness, Therapeutics, Biotech, Artificial intelligence (AI) and Machine Learning

Founded by experienced battery technologists and entrepreneurs, Mana Battery delivers on the promise of the sodium-ion battery with best-in-class cost and performance through a proprietary low-cost, fire-extinguishing electrolyte platform and a high-energy battery cell design that offers higher energy density than LFP Li-ion at half-the-cost. Visit the Mana Website

• Raising: Pre-Seed; $9.25 Million Seed
• Contact: Tyler Evans, tyler@manabattery.us
• Team: Tyler Evans*, Co-Founder, CEO; Nicholas Singstock, Co-Founder, CTO; Chunmei Ban (CU Boulder Paul M. Rady Mechanical Engineering), Co-Founder, Chief Scientific Advisor; Douglas Campbell, Member of the Board of Directors; Heather A.S. Platt, Director of Materials Engineering and R&D; Peter Hosbein, Senior Cell Engineer; Salma Lira, Associate Cell Engineer; Ed Williams, Senior Business Advisor
• Affiliation: University of Colorado Boulder
• Industry Applications: Advanced Materials, Cleantech, Manufacturing

OMC Thermochemistry offers a low-cost, massively scalable route for the efficient, highly durable production of hydrogen or the transformation of CO₂ back into useful fuels and chemicals using heat, a novel active material, and globally abundant resources within existing industrial formats and competencies. Visit the OMC Website

• Raising: $15 Million Series A
• Contact: Britt Boughey, britt@omch2.com
• Team: Kent Warren (CU Boulder Chemical and Biological Engineering), Co-Founder, CSO; Britt Boughey, Co-Founder, CEO; Patrick Vincent, Senior Process Engineer
• Affiliation: University of Colorado Boulder
• Industry Applications: Aerospace, Advanced Materials, Environment and Sustainability, Cleantech, Chemicals

Otoro Energy is revolutionizing long-duration energy storage with a high-efficiency, low-cost flow battery. Backed by the largest U.S. utility and over $6 million in DOE grants, our non-flammable, non-toxic technology enables safe, 10+ hour discharge, delivering reliable, scalable and cost-effective grid resilience. Visit the Otoro Website

• Raising: $4 Million Seed
• Contact: Michael Marshak, mike@otoroenergy.com
• Team: Michael Marshak (frm. CU Boulder Chemistry, RASEI)
• Affiliation: University of Colorado Boulder
• Industry Applications: Cleantech, Hardware and Instrumentation

PAGE Technologies is redefining agricultural and environmental monitoring with a breakthrough analytics platform. Our proprietary printed electronics deliver real-time, ultra-low-cost data collection. With seamless API integration, PAGE enables strategic partners to scale impact and unlock new revenue opportunities. Visit the PAGE Website

• Raising: $3 Million Seed
• Contact: Elliot Strand, elliot@pagetechnologies.io
• Team: Elliot Strand* (CU Boulder College of Engineering and Applied Science), Co-Founder, CEO; Payton Goodrich, Co-Founder, CTO; Cameron Handeland, Lead Systems Engineer
• Affiliation: University of Colorado Boulder
• Industry Applications: Advanced Materials, Artificial Intelligence (AI) and Machine Learning, Environment and Sustainability, Cleantech, Food and Agriculture, Sensors

Paramium is an aerospace telecom company focused on building a global network of advanced ground stations for multiband satellite connectivity. Its centralized system simplifies scheduling, connection, downloading and mission control, much like scheduling an online conference. Visit the Paramium Website

• Raising: $5 Million Seed
• Contact: Justin Hyatt, jhyatt@paramium.com
• Team:Justin Hyatt, CEO, Co-Founder; Christian Davila*, CTO, Co-Founder; Ken Gyure (University of Arizona Eller College of Management), COO, Michael Martin, CFO
• Affiliation: University of Arizona
• Industry Applications: Aerospace

TheraCea Pharma is a biotechnology company dedicated to developing a new generation of radiopharmaceutical compounds as theranostics, molecules that have both diagnostic and therapeutic applications, and advanced diagnostics for detecting and treating cancers and neurological disorders. Visit the TheraCea Website

• Raising: $1.125 Million Pre-Seed
• Contact: Iman Daryaei, idaryaei@theracea.com
• Team: Iman Daryaei*, CEO, Co-Founder; Pavel Rychetsky, Vice President of R&D; David Loynd, Fractional CFO; Justin Jeffery, Chief Business Officer; Rikki Waterhouse, Regulatory Affairs Consultant; Julian Dresler, Manager of R&D; Nathan Wright, Manager of Business Operations; Jacob Fussell, Scientist II; Caleb Brown, Business Intelligence Officer
• Affiliation: University of Arizona
• Industry Applications: Therapeutics, Diagnostics, Biotech

Tynt’s platform technology enables real-time dynamic tinting through reversible metal electrodeposition (RME). It’s tunable by application, integrates into glass or plastic, has a wide dynamic range, neutral color, low cost and is flexible, unlocking new possibilities for smart materials. Visit the Tynt Website

• Raising: $15-20 Million Series A
• Contact: Ameen Saafir, ameen@tynt.io
• Team: Ameen K. Saafir*, CEO; John Dwyer, COO; Tyler Hernandez, CTO; Michael McGehee, Chief Scientist
• Affiliation: University of Colorado Boulder
• Industry Applications: Advanced Materials, Augmented Reality (AR) and Virtual Reality (VR), Environment and Sustainability, Cleantech, Smart Cities