Institute for Behavioral Genetics
University of Colorado Boulder
447 UCB
Boulder, CO 80309-0447
Research Interests:
The use of genetic strategies to identify the underlying biological bases for the behavioral and physiological actions of drugs of abuse with special emphasis on nicotine.
Active Grants:
- NIDA U01DA043802 (Stitzel, JA, Radcliffe, RA) 4/1/18-12/31/22. Genetic modifiers of Chrna5 deletion in mice: role in nicotine behaviors modulated by the medial habenula-IPN pathway. Role: PI
- NIDA R01DA044283 (Vrieze, S). Deep sequencing, phenotyping, and imputation in large-scale biobanks: a novel and cost-effective framework to identify rare mutations associated with addiction. Role: Co-investigator
-
AB Nexus Grant (Stitzel, Patel MPI). Multi-generation impact of developmental nicotine exposure on mitochondrial function. Role: Lead PI
Additional Resources:
Molecular Neurogenetics Laboratory
Current lab
Former Trainees
Jennifer Wilking
Doctoral student
2005-2009
Sheila Maier
Masters student
2006-2008
Tristan McClure-Begley
Doctoral student
2008-2010
Janessa Jacobs
Masters student
2008-2010
William Horton
Doctoral student
2009-2013
Hunter Mathews
Doctoral student
2014-2020
Jordan Buck
Doctoral student
2016-2020
Amanda Alvarado
Masters student
2017-2019
Xiao Li
Postdoctoral trainee
2002-2003
Sharon Mexal
Postdoctoral trainee
2005-2007
Tom Precht
Postdoctoral trainee
2008-2010
Anne Tammamaki
Postdoctoral trainee
2009-2012
Cristian Zambrano
Postdoctoral trainee
2009-2012, 2015-2017
Andre Zalud
Postdoctoral trainee
2011-2014
Rebecca Helfand
Postdoctoral trainee
2011-2014
Peter Dobelis
Postdoctoral trainee
2015-2017
Heidi O'Neill
Postdoctoral trainee
2015-2019
The β3 nicotinic receptor subunit:: A component of α-conotoxin MII-binding nicotinic acetylcholine receptors that modulate dopamine release and related behaviors
Cui CH; Booker TK; Allen RS; Grady SR; Whiteaker P; Marks MJ; Salminen O; Tritto T; Butt CM; Allen WR...
- Cui CH
- Booker TK
- Allen RS
- Grady SR
- Whiteaker P
- Marks MJ
- Salminen O
- Tritto T
- Butt CM
- Allen WR
Publication Date: 2003-12-03
Type: Journal Article
Identification of an alternatively processed nicotinic receptor alpha 7 subunit RNA in mouse brain
Publication Date: 2003-09-10
Type: Journal Article
The mouse Chrna4 A529T polymorphism alters the ratio of high to low affinity alpha 4 beta 2 nAChRs
Publication Date: 2003-09-01
Type: Journal Article
A polymorphism in the alpha 4 nicotinic receptor gene (Chrna4) modulates enhancement of nicotinic receptor function by ethanol
Publication Date: 2003-05-01
Type: Journal Article
A polymorphism in the mouse neuronal alpha 4 nicotinic receptor subunit results in an alteration in receptor function
Publication Date: 2002-08-01
Type: Journal Article
Variability in response to nicotine in the LSxSS RI strains: potential role of polymorphisms in alpha(4) and alpha(6) nicotinic receptor genes
Publication Date: 2002-04-01
Type: Journal Article
Potential regulation of nicotine and ethanol actions by alpha 4-containing nicotinic receptors
Publication Date: 2001-06-01
Type: Journal Article
Long sleep and short sleep mice differ in nicotine-stimulated Rb-86(+) efflux and alpha(4) nicotinic receptor subunit cDNA sequence
Publication Date: 2001-06-01
Type: Journal Article
Genetic and pharmacological strategies identify a behavioral function of neuronal nicotinic receptors
Publication Date: 2000-08-01
Type: Journal Article
Potential role of the alpha 4 and alpha 6 nicotinic receptor subunits in regulating nicotine-induced seizures
Publication Date: 2000-04-01
Type: Journal Article
Nicotinic-agonist stimulated Rb-86(+) efflux and [H-3]epibatidine binding of mice differing in beta 2 genotype
Publication Date: 2000-01-01
Type: Journal Article
Two pharmacologically distinct components of nicotinic receptor-mediated rubidium efflux in mouse brain require the beta 2 subunit
Marks MJ; Whiteaker P; Calcaterra J; Stitzel JA; Bullock AE; Grady SR; Picciotto MR; Changeux JP; Collins AC...
- Marks MJ
- Whiteaker P
- Calcaterra J
- Stitzel JA
- Bullock AE
- Grady SR
- Picciotto MR
- Changeux JP
- Collins AC
Publication Date: 1999-05-01
Type: Journal Article
Genetic Regulation of Nicotine-Related Behaviors and Brain Nicotinic Receptors
Type: Chapter
Sensitivity to the seizure-inducing effects of nicotine is associated with strain-specific variants of the alpha 5 and alpha 7 nicotinic receptor subunit genes
Publication Date: 1998-03-01
Type: Journal Article
Inheritance of a schizophrenia-like deficit in auditory gating fits - A one gene model in inbred mouse strains
Publication Date: 1997-03-01
Type: Conference Proceeding
Linkage of strain-specific nicotinic receptor alpha(7) subunit restriction fragment length polymorphisms with levels of alpha-bungarotoxin binding in brain
Publication Date: 1996-12-31
Type: Journal Article
Chronic corticosterone treatment elicits dose-dependent changes in mouse brain alpha-bungarotoxin binding
Publication Date: 1996-06-01
Type: Journal Article
DIFFERENCES IN RESPONSE TO NICOTINE ARE DETERMINED BY GENETIC-FACTORS
Type: Chapter
GENETIC INFLUENCES ON NICOTINE RESPONSES
Publication Date: 1989-07-01
Type: Journal Article
AN AUTORADIOGRAPHIC ANALYSIS OF CHOLINERGIC RECEPTORS IN MOUSE-BRAIN
Publication Date: 1989-02-01
Type: Journal Article
NICOTINE EFFECTS IN INBRED MOUSE STRAINS
Publication Date: 1988-03-25
Type: Journal Article
SULFHYDRYL MODIFICATION OF 2 NICOTINIC BINDING-SITES IN MOUSE-BRAIN
Publication Date: 1988-03-01
Type: Journal Article
INFLUENCE OF KINETICS OF NICOTINE ADMINISTRATION ON TOLERANCE DEVELOPMENT AND RECEPTOR LEVELS
Publication Date: 1987-07-01
Type: Journal Article
AUTORADIOGRAPHIC ANALYSIS OF NICOTINIC RECEPTORS IN MOUSE-BRAIN
Publication Date: 1987-04-01
Type: Journal Article
DISULFIDE MODIFICATION OF NICOTINIC BINDING-SITES IN MOUSE-BRAIN
Publication Date: 1987-03-01
Type: Journal Article
Pages
Recruiting
Dr. Stitzel is recruiting new students for a fall 2025 start date. Applications are typically due mid November; for exact dates please check the Department of Integrative Physiology website, if you intend to work with Dr. Stitzel. Additional information is available on IBG's Prospective Students page.
The Stitzel lab is not currently recruiting postdocs.